It is my view that this sort of thing is not really helpful to any sort of a campaign for President. While Senator Rubio might not be responsible for this activity attacking Mr. Trump, somehow I think such ads over a California audience isn't going to do anything to attract voters to the GOP.
Further, it just focuses negativity. Conservative philosophy is inherently superior to Progressive Liberalism. If we are to win this election it will be by spreading the message of limited government and promotion of freedom according to our Constitution. Not by candidates bashing and insulting one another.
Not to mention that if the aim was to humiliate Donald Trump...I don't think anything like this works. In fact I won't be surprised if it emboldens him.